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D-Glutamic acid
CAS No. 6893-26-1
D-Glutamic acid( (R)-Glutamic acid )
Catalog No. M24704 CAS No. 6893-26-1
D-glutamic acid, the enantiomer of L-glutamic acid, is widely used in medicine and food.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 35 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameD-Glutamic acid
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NoteResearch use only, not for human use.
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Brief DescriptionD-glutamic acid, the enantiomer of L-glutamic acid, is widely used in medicine and food.
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DescriptionD-glutamic acid, the enantiomer of L-glutamic acid, is widely used in medicine and food.
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In VitroVarious d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.
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In VivoD-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.
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Synonyms(R)-Glutamic acid
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number6893-26-1
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Formula Weight147.13
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Molecular FormulaC5H9NO4
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Purity>98% (HPLC)
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SolubilityH2O:10 mg/mL (67.97 mM; Need ultrasonic)
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SMILESN[C@H](CCC(O)=O)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Han H, et al. Changes in D-aspartic acid and D-glutamic acid levels in the tissues and physiological fluids of mice with various D-aspartate oxidase activities. J Pharm Biomed Anal. 2015 Dec 10;116:47-52.
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